@article {962,
	title = {Toxoplasma gondii primary infection in renal transplant recipients. Two case reports and literature review},
	journal = {Transpl Int},
	volume = {24},
	year = {2011},
	note = {Martina, Maria-Noel Cervera, Carlos Esforzado, Nuria Linares, Laura Torregrosa, Vicenc Sanclemente, Gemma Hoyo, Irma Cofan, Federico Oppenheimer, Federico Miro, Jose M Campistol, Jose Maria Moreno, Asuncion Research Support, Non-U.S. Gov{\textquoteright}t England Transplant international : official journal of the European Society for Organ Transplantation Transpl Int. 2011 Jan;24(1):e6-12. doi: 10.1111/j.1432-2277.2010.01173.x. Epub 2010 Oct 19.},
	month = {Jan},
	pages = {e6 - 12},
	edition = {40471},
	abstract = {Toxoplasmosis after solid organ transplantation is a complication associated with high morbidity and mortality. Universal prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMX) is effective to prevent post-transplant toxoplasmosis. We report two cases of renal transplant recipients with negative antibodies against Toxoplasma gondii pretransplant who developed toxoplasmosis after TMP-SMX discontinuation. We have also performed a review of published cases of primary toxoplasmosis after renal transplantation. Of 20 cases reviewed, 11 were male and the mean age was 37.8 years (SD = 13.8). Donor serology for T. gondii was determined in 15 donors, two of them (13\%) with negative immunoglobulin (Ig)G and four (27\%) with positive IgG and IgM antibodies. Fever was present in 85\% of primary toxoplasmosis and hematologic abnormalities were observed in 69\% of the cases. Ten patients died (50\%). All patients with fatal outcomes had clinical evidence of toxoplasmosis during the early post-transplant period (first 90 days), while no patient with late toxoplasmosis died (P = 0.003). Primary toxoplasmosis is associated with high mortality rates and TMP-SMX prophylaxis can delay the onset of symptoms resulting in an improvement of prognosis.},
	issn = {1432-2277 (Electronic) 0934-0874 (Linking)},
	doi = {10.1111/j.1432-2277.2010.01173.x},
	author = {Martina,M. N. and Cervera,C. and Esforzado,N. and Linares,L. and Torregrosa,V. and Sanclemente,G. and Hoyo,I. and Cofan,F. and Oppenheimer,F. and Miro,J. M. and Campistol,J. M. and Moreno,A.}
}
