@article {905,
	title = {[Vertical transmission of hepatitis C virus infection]},
	journal = {Di Yi Jun Yi Da Xue Xue Bao},
	volume = {23},
	year = {2003},
	note = {Li, Min-min Liu, Shu-wen Wang, Shan-shan Wang, Xiao-ning English Abstract Research Support, Non-U.S. Gov{\textquoteright}t China},
	month = {Dec},
	pages = {1290 - 2},
	edition = {37973},
	abstract = {OBJECTIVE: To investigate the mechanism for vertical transmission of hepatitis C virus (HCV) infection. METHODS: This study included 6 pairs of mothers and fetuses who were positive for anti-HCV antibody and HCV RNA, and 2 pairs of fathers and fetus in whom the father was positive for anti-HCV and HCV RNA while the mother was negative. HCV genotypes were detected by PCR and the nucleotide sequences of HCV genome spanning the core and envelope gene region (HCV C/E1) determined and compared. RESULTS: The HCV genotypes of the mothers and fetus were consistent. Five mother-fetus pairs were of genotype II, 1 of genotype III, with high homology of HCV between the mothers and their own fetuses. In contrast, in the two father-fetus pairs, no HCV RNA was detected in the fetuses in spite of the positivity of the fathers. CONCLUSION: Vertical transmission of HCV infection from mothers to fetus is a clinical entity.},
	keywords = {*Infectious Disease Transmission, Vertical, Female, Genotype, Hepatitis C / *transmission, Hepatitis C Antibodies / blood, Humans, Male, Pregnancy, RNA, Viral / blood},
	issn = {1000-2588 (Print) 1000-2588 (Linking)},
	author = {Li,M. M. and Liu,S. W. and Wang,S. S. and Wang,X. N.}
}
