@article {799,
	title = {Infectious complications in living-donor liver transplant recipients: a 9-year single-center experience},
	journal = {Transpl Infect Dis},
	volume = {10},
	year = {2008},
	note = {Kim, Y J Kim, S I Wie, S H Kim, Y R Hur, J A Choi, J Y Yoon, S K Moon, I S Kim, D G Lee, M D Kang, M W Denmark Transplant infectious disease : an official journal of the Transplantation Society Transpl Infect Dis. 2008 Oct;10(5):316-24. Epub 2008 May 26.},
	month = {Oct},
	pages = {316 - 24},
	edition = {39598},
	abstract = {BACKGROUND: Infectious complications following living-donor liver transplantation (LDLT) remain a major cause of morbidity and mortality. We analyzed the frequency and type of infectious complications according to the post-transplantation period, and their risk factors with regard to morbidity and mortality. METHODS: We retrospectively analyzed 208 subjects who had undergone LDLT during a 9-year period. RESULTS: The rate of infection was 1.69 per patient during the study period. The predominant infections were intra-abdominal infections (37.6\%), primary bacteremia (17.4\%), and pneumonia (14.5\%). Within the first post-transplant month, 140 (39.9\%) infections were detected, and catheter-related coagulase-negative staphylococci (44) were the most common infectious agents. During the 2-6-month post-transplant period, 109 infectious episodes occurred (31.1\%), and Enterococcus sp. (n=16) related to biliary infection was the most frequent isolate. After the sixth month, 96 infectious episodes (29\%) occurred, and biliary tract-related Escherichia coli (n=19) was the major causative organism. The overall mortality was 24.5\% (51/208); 1-year survival rate was 88\% (196/208). Post-transplant infection-related mortality was 52.9\% (27/51). Biliary tract complications, such as biliary stenosis or leakage, significantly increased the mortality (P=0.01); however, reoperation (retransplantation or resurgery for biliary tract obstruction/leakage or to control bleeding) significantly reduced the mortality (P=0.01). CONCLUSIONS: Our data showed that early catheter removal would mainly aid in reducing infectious complications in the 1-month post-transplantation period. Aggressive management, including reoperation, would lower the mortality in the LDLT recipients.},
	keywords = {*Living Donors, Bacteremia / epidemiology / etiology / mortality, Biliary Tract Diseases / epidemiology / etiology / mortality, Female, Humans, Infection / *epidemiology / etiology / mortality, Korea / epidemiology, Liver Transplantation / *adverse effects, Male, Middle Aged, Peritonitis / epidemiology / etiology / mortality, Pneumonia / epidemiology / etiology / mortality, Postoperative Complications / *epidemiology / etiology / mortality, Reoperation, Retrospective Studies, Risk Factors, Survival Rate, Time Factors, Transplantation Conditioning / *adverse effects},
	issn = {1399-3062 (Electronic) 1398-2273 (Linking)},
	doi = {TID315 [pii] 10.1111/j.1399-3062.2008.00315.x},
	author = {Kim,Y. J. and Kim,S. I. and Wie,S. H. and Kim,Y. R. and Hur,J. A. and Choi,J. Y. and Yoon,S. K. and Moon,I. S. and Kim,D. G. and Lee,M. D. and Kang,M. W.}
}
