@article {222, title = {Post-corneal transplant tumors of nondonor origin in the anterior chamber of the eye: a case report}, journal = {Cornea}, volume = {17}, year = {1998}, note = {Brederhorn, T Gorsira, M C Volker-Dieben, H J Case Reports United states Cornea Cornea. 1998 Mar;17(2):212-4.}, month = {Mar}, pages = {212 - 4}, edition = {35885}, abstract = {PURPOSE: To investigate whether post-corneal transplant tumors are of donor origin, we studied the case of a 29-year-old female corneal transplant recipient who developed tumors in the anterior chamber on the iris of her right eye 7 years after transplantation. METHODS: Because the corneal graft donor was a 53-year-old man whose cause of death was reported as heart failure but who had uremia secondary to a metastatic Grawitz{\textquoteright}s tumor, transmission of his malignancy had to be excluded. One of the patient{\textquoteright}s iris tumors was removed through an incision in the cornea for examination to establish the diagnosis. RESULTS: The histological examination of the iris mass showed the typical picture of a noncaseous epithelioid cell granuloma compatible with the diagnosis of sarcoidosis. The observed post-corneal transplant tumor was clearly not of donor origin. Nevertheless, when tumor growth is observed in an eye after corneal transplantation, transmission of a malignancy has to be excluded. To the best of our knowledge, this is the first report of sarcoidosis with iris nodules after corneal transplantation. CONCLUSION: Our case report illustrates the importance of keeping reliable medical histories of graft donors and of their use in establishing whether post-transplant tumors are of donor origin. The long-term storage of donor medical records should be recommended because of the importance of being able to access that information even years after transplantation.}, keywords = {*Tissue Donors, Adult, Anterior Chamber / *pathology, Carcinoma, Renal Cell / pathology, Diagnosis, Differential, Female, Granuloma / etiology / *pathology, Humans, Iris Diseases / etiology / *pathology, Keratoplasty, Penetrating / *adverse effects, Kidney Neoplasms / pathology, Male, Middle Aged, Postoperative Complications / *pathology, Sarcoidosis / etiology / *pathology}, issn = {0277-3740 (Print) 0277-3740 (Linking)}, doi = {00003226-199803000-00017 [pii]}, url = {internal-pdf://Brederhorn - post corneal transplant tumors-0565814016/Brederhorn - post corneal transplant tumors.pdf}, author = {Brederhorn,T. and Gorsira,M. C. and Volker-Dieben,H. J.} }