@article {146,
	title = {Recurrent seizure and sustained encephalopathy associated with dimethylsulfoxide-preserved stem cell infusion},
	journal = {Leukemia \& lymphoma},
	volume = {46},
	year = {2005},
	note = {Bauwens, Deborah Hantson, Philippe Laterre, Pierre-Francois Michaux, Lucienne Latinne, Dominique},
	month = {Nov},
	pages = {1671 - 4},
	type = {Case Reports},
	edition = {38646},
	abstract = {We report the case of a patient who received two infusions of dimethylsulfoxide (DMSO) cryopreserved autologous peripheral blood progenitor cells (PBPCs) after myeloablative chemotherapy for a relapsing lymphoma. A 49-year-old man presented an episode of tonic-clonic seizure over a few minutes after the start of each infusion and developed a profound and sustained but reversible encephalopathy with coma after the second infusion. The patient{\textquoteright}s neurological condition correlated well with the electrophysiological findings (electroencephalogram and multimodality evoked potentials) and, to a lesser extent, with the radiological abnormalities (magnetic resonance imaging). Severe but reversible neurological complications may occur with the infusion of PBPCs cryopreserved with DMSO.},
	keywords = {Cryopreservation / methods, Dimethyl Sulfoxide / *adverse effects, Fatal Outcome, Humans, Lymphoma, Large B-Cell, Diffuse / complications / therapy, Male, Neurotoxicity Syndromes / *etiology, Peripheral Blood Stem Cell Transplantation / *adverse effects, Recurrence, Seizures / *chemically induced, Tissue Preservation / methods},
	issn = {1042-8194 (Print) 1026-8022 (Linking)},
	doi = {10.1080/10428190500235611},
	author = {Bauwens,D. and Hantson,P. and Laterre,P. F. and Michaux,L. and Latinne,D. and De Tourtchaninoff,M. and Cosnard,G. and Hernalsteen,D.}
}
