@article {99,
	title = {Leukaemic relapse of donor origin after allogeneic bone marrow transplantation from a donor who later developed bronchogenic carcinoma},
	journal = {Br J Haematol},
	volume = {119},
	year = {2002},
	note = {0007-1048 (Print) Case Reports Journal Article},
	month = {Dec},
	pages = {777 - 80},
	abstract = {Donor-derived leukaemia is exceptional after allogeneic bone marrow transplantation (BMT). A woman with chronic myeloid leukaemia received an allogeneic BMT from a human leucocyte antigen-identical brother. The donor, a 50-year-old non-smoker, died of squamous cell bronchogenic carcinoma 1 year later. At 4 years post BMT, the patient became BCR/ABL positive and relapsed with acute myeloid leukaemia, which was shown to be donor-derived cytogenetically and molecularly. Retrospective analysis showed that the donor-leukaemic clone had started to evolve as early as 6 months post BMT. Sequencing of p53 ruled out Li-Fraumeni syndrome. Predisposition to malignancy might be an underlying mechanism of donor-cell leukaemia.},
	keywords = {Acute Disease, Bone Marrow Transplantation / *adverse effects, Carcinoma, Bronchogenic / complications, Fatal Outcome, Female, Humans, Leukemia, Myeloid / *etiology / genetics, Leukemia, Myeloid, Philadelphia-Positive / therapy, Lung Neoplasms / complications, Male, Middle Aged, Pedigree, Recurrence, Research Support, Non-U.S. Gov{\textquoteright}t, Smoking / adverse effects, Tissue Donors, Transplantation, Homologous},
	author = {Au,W. Y. and Chan,E. C. and Siu,L. L. and Lau,T. C. and Lie,A. K. and Ma,S. K. and Kwong,Y. L.}
}
