Occurrence of multiple myeloma in both donor and recipient after bone marrow transplantation

TitleOccurrence of multiple myeloma in both donor and recipient after bone marrow transplantation
Publication TypeJournal Article
Year of Publication2002
AuthorsKumar A, Styler MJ, Topolsky DL, Crilley PA, Przybysz TM, Gladstone DE
JournalAm J Hematol
Volume71
Issue3
Pagination227 - 8
Date PublishedNov
ISSN0361-8609 (Print) 0361-8609 (Linking)
Accession Number12410583
Keywords*Tissue Donors, Adult, Bone Marrow Transplantation / *adverse effects, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive / *surgery, Male, Multiple Myeloma / *etiology
Abstract

The transplantation of malignant cells during allogeneic transplant is a rare occurrence. 27 months after donating progenitor cells, a diagnosis of multiple myeloma was made in a 6/6 HLA-phenotypically matched unrelated donor. The 42-year-old recipient transplanted for chronic phase chronic myeloid leukemia developed IgA myeloma 40 months after transplantation. Serum electrophoresis and bone marrow investigations established the diagnosis of IgA K multiple myeloma in both. This case illustrates the natural history and biology of multiple myeloma.

DOI10.1002/ajh.10239
Notify Library Reference ID845

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