Sustained cytopenia after leukapheresis for collection of peripheral blood stem cells in small children

TitleSustained cytopenia after leukapheresis for collection of peripheral blood stem cells in small children
Publication TypeJournal Article
Year of Publication1989
AuthorsTakaue Y, Watanabe T, Kawano Y, Koyama T, Abe T, Suzue T, Shimokawa T, Ninomiya T, Kuroda Y
JournalVox Sanguinis
Volume57
Issue3
Pagination168 - 71
Keywords*Hematopoietic Stem Cell Transplantation, *Leukapheresis / ae [Adverse Effects], *Leukemia, T-Cell / th [Therapy], *Leukopenia / et [Etiology], *Neuroblastoma / th [Therapy], Child, Preschool, Clinical Protocols, Female, Hematopoiesis / ph [Physiology], Hematopoietic Stem Cells / ph [Physiology], Humans, Leukemia, T-Cell / dt [Drug Therapy], Male, Neuroblastoma / dt [Drug Therapy], Recurrence
Abstract

Marked and persistent cytopenia was observed in two 3-year-old children with cancer, after lymphopheresis to collect peripheral blood stem cells (PBSC) for autotransplantation after high-dose chemotherapy. This finding suggests that PBSC are a major component of the hematopoietic cells in small children and, hence, that special care is necessary in the construction of a protocol for collection of stem cells from young children.

Short TitleSustained cytopenia after leukapheresis for collection of peripheral blood stem cells in small children
Notify Library Reference ID1518

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